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This is totally reshaping how we design and conduct clinical trials. As an alternative of merely testing a drug on a blended group of individuals researchers can now choose members based mostly on their particular genetic make-up a course of referred to as affected person stratification. For example, as an alternative of working a big trial for a basic kind of cancer, we will now establish and enroll solely these patients whose cancer is brought on by a particular gene mutation. By doing this we will instantly take a look at if a drug works on the foundation trigger of the illness quite than simply treating the signs. This focused strategy not solely makes trials smaller and extra environment friendly, nevertheless it additionally dramatically will increase the probability of success. It represents a elementary and hopeful shift from treating a illness to treating the precise model of that illness in a selected particular person the insights we achieve from genomics are really enabling a brand new simpler approach of creating therapies.
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